Microfluidics
The concept of microfluidics
Flow cells for DNA sequencing are microfluidic devices designed to capture and process DNA molecules for high-throughput sequencing. They contain nanostructured wells where DNA fragments are immobilized and sequenced in parallel. These cells enable real-time monitoring of biochemical reactions, enhancing speed, accuracy, and scalability in sequencing technologies. Key advancements focus on increasing read length, sensitivity, and cost-effectiveness.
SEM images of the surfaces prepared by NIL from Solnil resin and technology, showing a square array of 200 nm bowl wells. The pattern is made of non-bonding highly transparent material. The bonding material (TiO2) is selectively deposited at the bottom of the wells after the imprinting process using a Solnil patented liquid deposition method. The SEM image on the right reveals DNA blobs trapped in each one of the wells. Such patterns can be processed on large surfaces of glass, Si, quartz,…The stability in relevant biologic analysis liquids (cycling and static modes) has been qualified.
Why is it different?
Performance and practical usage
Transparent hydrophobic SiO2
Refractive index = 1.42
Absorption < 0.1% (RGB)
Large surface (200 mm)
Glass or plastic substrates
Down to 200 nm entropic traps / square or hexagonal arrays
On demand trap’s aspect ratio from 0.1 to 2.
Are you developing the optics of the future?
This is what solnil does.
To discuss your technical needs or to initiate a collaboration, contact our team.